A Cluster Relating to Lipopolysaccharide Biosynthesis

Consider the following cluster. There are several things to note. First, look at the red genes numbered 1. Are they Phosphatidate cytidyltransferase as some of them are annotated? Note that the greenish-blue genes numbered 8 are annotated as Phosphatidate cytidylyltransferase (EC 2.7.7.41), as well.

Then there is the really strong clustering with the genes numbered 4 and 6. Further, some of the other genes are from the KDO2-Lipid A biosynthesis, some from Fatty_Acid_Biosynthesis_FASII, and some from Outer membrane. Integrating this into a coherent picture will be extremely difficult, I would imagine.