A Strange Cluster: No Clues
It seems to me that there is no overwhelming evidence that clustering
on the chromosome is almost always meaningful when proximity is
maintained for more than just a few diverse genomes. However,
sometimes one does encounter clusters for which no functional
relationships between members of the cluster spring to mind. This
cluster is one of those.
The cluster between the following genes is conserved through numerous
genomes:
- LSU ribosomal protein L25p,
- Peptidyl-tRNA hydrolase (EC 3.1.1.29), and
- Ribose-phosphate pyrophosphokinase (EC 2.7.6.1).
There is more to the cluster than just these three, but those three
offer a pretty difficult puzzle by themselves.